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- glucans, such as lentinan, schizophyllan, scleroglucan, and grifolan extracted from mushrooms, have been studied for controlling CRC via modulation of gut microbiota and regulation of immune genes (223, 277) (Table 3)

Intrinsic factor production often decreases with aging

doi: 10.1016/j.jaut.2022.102873 212 SiegelCHSammaritanoLR

UBX0101 (MDM2 inhibitor, Unity Biotechnology) targeted p53-MDM2 interaction in senescent cellsPhase 2 for knee OA failed in 2020